Hypoglycemic effect of acacia tortilis (100 mg/kg orally) gum extracted from seeds was evaluated in normal as well as alloxan (150 mg/kg body weight intraperitoneally) induced diabetic rats. Blood sugar levels (fasting & after oral glucose tolerance test) in normal rats were reduced after acacia torticollis gum (100 mg/kg orally) administration. Similar results were obtained when gum was administered to alloxon diabetic rats at different time intervals (0, 1 & 2 hr). Piogliotazone (4 mg/kg oral) was more potent than acacia tortilis gum in reducing blood sugar levels in alloxan diabetic rats.
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